Evaluation of a probabilistic model for staging of oesophageal carcinoma.

With the help of two experts in gastrointestinal oncology from the Netherlands Cancer Institute, Antoni van Leeuwenhoekhuis, a decision-support system is being developed for patient-specific therapy selection for oesophageal carcinoma. The kernel of the system is a probabilistic model describing the characteristics of oesophageal carcinoma and the pathophysiological processes of invasion and metastasis. Using data from 185 patients, an evaluation study of the model was conducted. We found that for 86% of the patients, the model established the stage of the patient's carcinoma correctly.